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Monday, 3-Aug-2009 12:00 Email | Share | | Bookmark
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INTRODUCTION
Advancements in the field of science have a tremendous effect in the lifestyle of people around the world. The things which we were only conceiving in our minds a long time ago came into reality after years of research and testing of the greatest minds of every century. The pursuit for the elixir of life has become a race for most developed countries so a lot of them are investing a lot of money, time and effort just to bring quality life in every household around the globe, most especially to those who can afford.

With these evident realities at hand, it is undoubtedly a fact that aside from the prolonging of life span, production of goods which are luxurious and would give immediate satisfaction is also being held as a primary consideration. In medical science, one such thing that has brought so much change in the lifestyle of people is the manufacture of Viagra, a drug that has been popular among people of all ages and races for adding more color to one of the basic needs of humanity---sex.

BRIEF HISTORY
It is safe to remember that Viagra is not for everybody. Originally, Viagra was developed by Pfizer as a drug to help men who were suffering from chest pain. However, sildenafil citrate, the active ingredient of Viagra, as a heart medication did not show progress of attaining its purpose and studies were stopped in 1992. Yet, based on published information about some properties contained in sildenafil citrate, Pfizer researchers began to look at it as a treatment for erectile dysfunction. Erectile dysfunction can also be termed as impotence or the difficulty to have an erection or maintaining it among males. Re-evaluation for its effect on the ability of men with ED to engage in sexual activity, and the ability to achieve and maintain erection sufficient for satisfactory sexual activity was taken.

Later, the clinical trials conducted by the researchers found Viagra to be so effective that the FDA approved it only six months after submission, and without consulting an advisory committee of outside experts because there were no troubling questions and no significant side effects. In furtherance to its primary uses, Viagra is being tested against pulmonary hypertension in children and infertility in women.

HOW IT WORKS
Basically Viagra’s appearance is bluish, diamond-shaped tablets with 25mg, 50mg, or 100mg strengths embossed on one side, denoting tablet strength. It works by dilating blood vessels throughout the body, allowing blood to flow more readily to the heart, lungs and other organs. Moreover, Viagra relaxes smooth muscle contractions in the penis. Around 70 percent of men using it reported some improvement in achieving and maintaining an erection. Effects normally begin within 30 minutes and last about 4 hours.

Since Viagra is only for those who have erectile dysfunctions, the drug must be taken orally once a day, one hour before the sexual activity. Viagra is not meant to be taken regularly for a prolonged period. Just take it when you need it.

An important thing to remember also is, you should not take Viagra if you are using nitrate drugs to control angina pain because the combination of the nitrate drugs and Viagra can lower your blood pressure dangerously putting your life in danger. The combinations of drugs are life-threatening for you. If it gives you an allergic reaction, do not use it again. Also, if you have severe heart problems where sexual activity can be a danger to your life, do not take Viagra.

AFTER EFFECTS
Side effects of using Viagra include headache, flushed skin, and anxiety. Its serious risks can include distorted vision and priapism -- a painful, prolonged erection that may require medical intervention. Historically, 69 deaths were linked to Viagra during its first three months on the market so the U.S. Food and Drug Administration issued a warning against using it with amyl nitrate ("poppers"), nitroglycerin, and nitrous oxide since each dilates blood vessels, thus, a dangerous drop in blood pressure can result, leading to possible heart attack or stroke.

ADDICTIVE?
Probably yes. Firstly, men who take Viagra to obtain even greater pleasure from their sex life become so much used to the drug that they find their love life uninteresting without the use of Viagra, as compared to earlier. Secondly, to some men, the effect of Viagra may decrease with time hence these men are less likely to have a non Viagra erection as compared to earlier when they did not take Viagra. Moreover, some men with no performance problems except psychologically may take even far larger doses of the drug to satisfy their own perception of a satisfactory sexual performance.

CONCLUSION
With the facts given, the question now is, “Is it for you?” Think it over. Never rush.

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Monday, 3-Aug-2009 12:00 Email | Share | | Bookmark
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Kamagra (Generic Viagra) [sildenafil citrate], manufactured by Ajanta Pharma, Ltd, this drug is the first cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 enzyme inhibitor. This enzyme helps in regulating the blood circulation in the penile tissue. This leads to better penile erection.
Kamagra (Generic Viagra) is primarily indicated in the treatment of impotence [erectile dysfunction]

The compound sildenafil was synthesized in Pfizer’s research lab in Kent, England. Believe it or not, sildenafil was actually being studied for the treatment of hypertension and angina pectoris. Angina pectoris, or chest pain, caused by an insufficient supply of oxygen and decreased blood flow to the heart muscle. Angina is frequently the first sign of ischemic heart disease. However, during the phase 1 clinical trials, it was found that instead of having a remarkable action on angina, this drug was very effective in inducing penile erections, the main pathology behind erectile dysfunction.
The drug was patented in 1996, approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first oral treatment approved to treat erectile dysfunction in the United States
Needless to say, this drug has become a household hit.

Erectile dysfunction:
Erectile dysfunction (ED) is defined as the inability of a man to achieve or maintain an erection sufficient for his sexual needs or the needs of his partner
Erection of the penis during coitus or otherwise is a result of increase in the blood flow of the arteries of the penis and simultaneous relaxation of the smooth muscle of corpora cavernosum. This whole process is due to the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP in turn, relaxes smooth muscle and resulting in an increase in the blood flow to the corpus cavernosum.
In erectile dysfunction, enough blood does not flow in the arteries of the penis to cause a sufficient erection.
Causes of erectile dysfunction:
With reduced libido:
- hypogonadism
- depression
With intact libido:
- psychological problems, including anxiety
- vascular insufficiency [atheroma]
- neuropathic [diabetes mellitus, alcohol excess, multiple sclerosis]
- drugs [beta blockers, thiazide diuretics]
.An organic cause can be found out in about 50% of the cases of erectile dysfunction; the rest are either psychogenic in origin or are due to a psychiatric illness such as depression which requires appropriate drug treatment. Systemic diseases like chronic liver or kidney diseases and drug addiction are important causes and should be looked for. In case of any psychogenic problem, even the partner should be actively involved in the counseling therapy
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum of the penile tissue during sexual stimulation. Nitric oxide then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood. Kamagra (Generic Viagra) [sildenafil citrate] has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of nitric oxide, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
There are many types of PDE, each having varied function. The plus point of Kamagra (Generic Viagra) [sildenafil citrate] is that it is PDE 5 selective, though it can also act on the other types of PDE. In fact higher doses or plasma levels of the drug is thought to be associated with defects in color vision due to its action on PDE 6.
Kamagra (Generic Viagra) [sildenafil citrate] has a 4,000-fold selectivity for PDE5 versus PDE3, which is concerned with cardiac contractility.

Indications:
- Erectile dysfunction. This is the main indication whereas for the indications given below, sildenafil is not in the first line treatment regimen.
- pulmonary arterial hypertension
- prevention of high altitude pulmonary edema associated with altitude sickness
- treatment of benign prostatic hypertrophy [BPH]-associated lower urinary tract symptoms [LUTS]
Indications under investigation:
- Relieving female sexual dysfunction. Several studies have indicated the drug may be effective in improving libido and arousal in women taking selective serotonin uptake inhibitors (SSRIs)
- Treatment of infertility. Women who have had repeated failures with in vitro fertilization (IVF) due to poor development of the endometrium [tissue that lines the uterus] may benefit from treatment with vaginal suppositories containing sildenafil.
- Esophageal motility dysfunction (achalasia), since it can enhance nitric oxide production.

Contraindications:
- patients on nitric oxide drugs since sildenafil potentiate the hypotensive effects of nitrates, and its administration to patients who are using organic nitrates, either regularly and/or intermittently, in any form is therefore contraindicated.
- There is a degree of cardiac risk associated with sexual activity, especially in elderly people above the age of 60 years. There is increase incidence of mortality and morbidity with KAMAGRA (GENERIC VIAGRA) [sildenafil]
- Severe hepatic impairment (decreased liver function)
- Severe impairment in renal function
- Hypotension (low blood pressure)
- History of stroke or heart attack
- Hereditary degenerative retinal disorders (including genetic disorders of retinal phosphodiesterases)
Side effects:
The most commonly reported side effects of KAMAGRA (GENERIC VIAGRA) are headache, flushing of the face, upset stomach, and nasal congestion.
Other less common side effects include, but are not limited to:
• vision problems, including sensitivity to light, blurred vision, and a color tinge to vision
• urinary tract infection
• diarrhea
• dizziness
• rash
Dosage:
Administered in the dose of 50 mg one hour before the intended sexual activity. Based on effectiveness and toleration, it can be increased to 100 mg or decreased to 25 mg.

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Tuesday, 10-Mar-2009 05:34 Email | Share | | Bookmark
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Erectile dysfunction, or ED, is a common problem. More than 30 million men in the US and more than 2 million men in the UK have experienced ED. Often, if the problem does not improve on its own, men will accept it rather than report it to their doctor, out of fear or embarrassment. But for over a decade there have been prescription drugs that successfully treat ED in many men. The first of these drugs was Viagra, which was introduced in 1998. Levitra and Cialis followed. This article will discuss the generic version of Cialis, which is also called tadalafil.

Viagra, Levitra, and Generic Cialis, or tadalafil, are in a class of drugs called PDE5 blockers. The reason for blocking PDE5 to treat impotence is that PDE5 breaks down a chemical called cGMP, which is necessary for proper arterial blood flow to the penis. cGMP acts on smooth muscle tissue and on blood vessels, relaxing them and causing them to enlarge, or dilate. If there isn’t enough cGMP, then proper blood flow to the penis is restricted, and an erection cannot be achieved or maintained. Blocking PDE5 allows circulating levels of cGMP to remain high enough that blood flow to the penis is not compromised.

Generic ciallis or Tadalafil is different from Viagra and Levitra, because it has a half-life in the bloodstream of 17.5 hours. Viagra and Levitra have half-lives closer to 4 hours. What this means is, the effects of Generic Ciallis can extend for up to 36 hours. Many men find this convenient, because they can take the drug and have more spontaneous sexual activity. Because of this, Generic Ciallis has been nicknamed “The Weekend Pill” by some.

Tadalafil or Generic Ciallis dosage :
When prescribed to be taken on an “as needed” basis, tadalafil is prescribed in dosages of 10 mg and 20 mg. There is also another option that is available in Europe, and that is taking a low dose of Generic Ciallis – 2.5 mg – daily to cope with chronic ED.

What are side effects of tadalafil or Generic Ciallis?
Most side effects of Generic Ciallis are not severe enough to cause more than annoyance, and most disappear within a few hours. The most common side effect is headache, possibly caused by dilated blood vessels in the head. Other common side effects include stomach ache, diarrhea, runny nose, blurred vision, dizziness, and changed vision that makes things appear as if they have a blue tint to them.

There are side effects of Generic Ciallis, however, which require prompt medical attention, and which should always be reported to your doctor. Irregular heartbeat, fainting, sudden loss of hearing, sudden loss of vision, or an erection that lasts longer than four hours (a condition known as priapism) are side effects that require immediate medical treatment to prevent serious complications or lasting damage.

Should some men avoid taking Generic Ciallis of tadalafil?
There are some men who should not take Generic Ciallis. Men who are not in good enough general health for sexual activity should not take Generic Ciallis. Men who take drugs containing nitrates, such as nitroglycerine, should not take Generic Ciallis , nor should men who have had a heart attack, stroke, or arrhythmia within the past six months.

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Wednesday, 11-Feb-2009 06:30 Email | Share | | Bookmark
Generic Viagra


People affected by impotence tend to get depressed rapidly at the mere thought of their incapacities. It is however futile to hold oneself responsible for mistakes done in the past. It is better to begin looking for an adequate way out of the problem. The first step is to visit the doctor who will undertake a complete exam of your body. If the doctor then concludes that you have Erectile Dysfunction (ED), you need not panic as he will provide you with a treatment. You can then inquire about Generic Viagra and its effects on your body. Once the doctor gives you the go ahead to take Generic Viagra and has instructed you on the dosage, you can shop around for the best deals.

Generic Meds.com is a very popular supplier of generic drugs. This company is globally famous for offering very good quality generic drugs at very competitive prices. You can take a peek at their website and evaluate their offers and contrast them with the competition.

Why Choose Generic Viagra?

Generic Viagra is very popular among men with ED. Its active ingredient is sildenafil citrate, a tried and tested molecule that helps men get an erection.

Mode of Action of Generic Viagra

It increases blood flow to the penis so that it easily becomes erect when the person is aroused.

Safety Concerns

It is a completely trustworthy drug as it has undergone the FDA approval process and is given to patients only under medical supervision.

When not to take Generic Viagra

Generic Viagra should never be taken with medicines that contain nitrate. It is essential to discuss your other medical treatments with your doctor before taking Generic Viagra.

Adverse Effects

Like all medical drugs, there are some adverse effects that arise as a result of their consumption. These are however treatable and can be reduced. Some include:

• Minor effects—experienced by most consumers of Generic Viagra, these problems are temporary and tend to disappear after a few hours. Headache, backache, flushing and stuffy or runny nose are among the symptoms.
• Major effects—these are rarer and should be reported to your doctor as soon as they arise:
a. Vision impairment
b. Cyanopsia (blue tinge in vision)
c. Prolonged erection
d. Lowered blood pressure
e. Heart attacks
f. Strokes
g. Sudden hearing impairment

Additional Uses of Generic Viagra

Besides being a treatment for ED, Generic Viagra is used in various ways by people:

• In Sports—professional athletes use Generic Viagra to cause their arteries to dilate so that there is greater amount of nutrients that are brought to their muscles.
• Illicit uses—young adults mix Generic Viagra with illicit drugs such as ecstasy to obtain mixtures called “sextasy”. This can have fatal consequences.
• Uses in Gardening—Generic Viagra is often used in gardening to retard wilting of cut flowers.

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Cataogry : Men Health





Tuesday, 13-Jan-2009 05:25 Email | Share | | Bookmark
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Erectile dysfunction is considered as one of the common disease of men today. Due to many factors, there is an increase in the number of men suffering ED every year. Men ages 40 and above are the population that is prone to this condition. However, the launching of many products that treats ED makes this disease manageable.
The launching of kamagra enables most men having erectile dysfunction to enhance their sexual drive and endurance and finally overcome their erectile dysfunction. Kamagra contains Sildenafil Citrate which is a PDE-5 inhibitor hence allowing the blood to flow into the penis to allow erection. When a man is sexually aroused, it produces 2 chemicals, the cyclic GMP and phosphodiesterase type 5 (PDE-5). Cyclic GMP works on the muscles in arterial wall of the penis to relax, allowing the blood to flow and the phosphodiesterase type 5 (PDE-5) is responsible in decreasing erections.
Using Kamagra, just like other sildenafil citrate and drugs that treats erectile dysfunction can produce side effects. Oftentimes it is mild like stomach upset, headache and facial flushing but there are few cases of blurred vision and sensitivity to light. Take note of this, if you are experiencing nausea, dizziness or chest pain during intercourse, medical intervention is necessary without delay.
Medication containing nitrate was found out to be very dangerous if taken together with kamagra. It will cause a sudden drop of blood pressure that may result to more serious condition. It is necessary to be aware of the other medications you are taking before taking this drug. If you are suffering from kidney and liver disease, heart failure, allergies, and high or low blood pressure. It is very important to consult your doctor before taking this drug. There is a proper dosage base on your case that only your doctor can determine.
Today lots of men having erectile dysfunction shifted to Kamagra because it is the cheapest Sildenafil Citrate available in the market. Just like other brand it is also very effective in treating impotence. Generic has made a major change in prices of medicines. Kamagra is another generic product that gains positive comments from its users. It is available in tablet and oral jelly form.
Buying kamagra can be done through the internet. Generic Meds.com, an online pharmacy has made purchasing generic drugs convenient to the users. Visit this website and find out information about your medication. It is one of the trusted companies in terms of generic drugs distribution world wide.

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